PATIENT PRESENTATION MARKER 

Anxiety symptoms

What this marker measures

Presence/absence of clinically significant anxiety according to the General Anxiety Disorder 7-item (GAD-7). This does not constitute a diagnosis.

Health categories/Interpretations informed by this marker

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Clinical features

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‍● Psychosocial concerns: anxiety symptoms are a commonly-reported psychosocial factor that can affect quality of life.
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Interpreting the result

PRESENT
Questionnaire responses give a GAD-7 score of 10 or more, indicating clinically significant anxiety symptoms. 
NOT PRESENT
Questionnaire responses give a GAD-7 score below 10.

Patient management insights

clinical management
Consider mental health review in addition to reducing anxiety and depression, psychological therapies such as cognitive behavioural therapy and gut‐directed hypnotherapy may improve IBS symptoms.1–3
GRADE C

Tips for patients discussion

"Your questionnaire responses suggest you've been feeling quite anxious lately. This is very common, and because the gut and brain are closely connected, how you feel emotionally can affect your gut symptoms too. Getting some support for this could help with both, and we can talk about what might suit you." 

Source references for all clinical associations, interpretation definitions, and patient management insights on this card.

1. Black, C. J. et al. Efficacy of psychological therapies for irritable bowel syndrome: systematic review and network meta-analysis. Gut 69, 1441–1451 (2020). 
2. Anderson, E. J., Peters, S. L., Gibson, P. R. & Halmos, E. P. Comparison of digitally delivered gut-directed hypnotherapy program with an active control for irritable bowel syndrome. Am J Gastroenterol 120, 440–448 (2025). 
3. Lövdahl, J. et al. Nurse-administered gut-directed hypnotherapy for irritable bowel syndrome: a two-year follow-up study. United European Gastroenterol J 13, 1307–1317 (2025).