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Emegring marker Guide

Human DNA

Human DNA
Research Use Only
Most of the DNA in stool (>99%) is from microbes and only a small amount should be human. Sources of human DNA in stool can include mucus, shedding of epithelial cells, blood, or sample contamination from other body areas.
Marker summary
Most faecal DNA is microbial. Human DNA sources include mucus, epithelial cells, blood, or contamination during sampling. High levels may be associated with ulcerative colitis, colorectal cancer or C. difficile infection.

What are emerging markers?

The emerging markers provides microbial markers which have historically been of clinical interest. These markershave an emerging evidence base leading to uncertainty around their role in human health.All emerging markers are tagged Research Use Only. These markers have an emerging evidence base leading to uncertainty around their role in human health.

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THESE PRODUCTS ARE ONLY AVAILABLE FOR PURCHASE THROUGH A HEALTHCARE PROFESSIONAL.
1.The quantitative faecal occult blood, polymerase chain reaction (qPCR) and enzyme-linked immunosorbent assays (ELISA) used in the Microbiome Explorer range are diagnostic and are approved for clinical use.
2.The faeces pH assay used in the Microbiome Explorer range is for research use only and not to be used as a basis for diagnosis. The metagenomic assays used in the Microbiome Explorer range are to determine the microbiome populations and associated functional pathways in a faecal sample. The application is for research use only and not to be used as a basis for diagnosis. Learn more about the journey we are on to validate this gold-standard technology for clinical diagnosis and application.
3. The Microbiome Explorer range is intended for adults 18 years or older only.

Disclaimer:
The information provided on this site is for the use of qualified healthcare professionals. The information contained on this website is in no way to be taken as prescriptive or to replace the healthcare professionals duty of care and personalised care practices.

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Ammonia (urease) producing microbes

Metabolic

Research Use Only

The microbial enzyme urease breaks down the compound urea, a nitrogen waste product created by the body, into ammonia. The role of gut bacteria that produce the enzyme urease is currently not well understood.

Marker summary

The enzyme urease breaks down urea into ammonia. The role of microbial urease remains unclear.

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Ammonia (urease) producing microbes

Metabolic

Research Use Only

The microbial enzyme urease breaks down the compound urea, a nitrogen waste product created by the body, into ammonia. The role of gut bacteria that produce the enzyme urease is currently not well understood.

Marker summary

The enzyme urease breaks down urea into ammonia. The role of microbial urease remains unclear.